This page contains supplementary material for the article:
G.I. Choudhary, P. Fränti, Predicting Onset of Disease Progression Using Temporal Disease Occurrence Networks, International Journal of Medical Informatics (2023), doi: https://doi.org/10.1016/ j.ijmedinf.2023.105068

Disease Prediction





How Relative Risk is calculated:
N
Total number of patients
p(A) = num(A)/N
probability that a patient has a diagnosis A
p(B) = num(B)/N
probability that a patient has a diagnosis B
observed
Number of patients that have both diagnosis A and B. Where A happened before B.
expected = p(A)⋅p(B)⋅N
Relative Risk = observed/expected

Conditional probability:
p(B|A): If patient has diagnosis A, what is the probability that they also have diagnosis B. This takes temporal occurrence account that A happened before B.